Publications

Independent

(40) Excitation- and emission wavelength-based multiplex spectroscopy using red-absorbing near infrared-emitting lanthanide complexes. Xiong, R.; Mara, D.; Liu, J.; Van Deun, R.; Borbas, K. E.  J. Am. Chem. Soc. 2018, 140,10975-10979.

(39) Lanthanide-based tools for the investigation of cellular environments. Mathieu, E.; Sipos, A.; Demeyere, E.; Phipps, D.; Sakaveli, D.; Borbas, K. E. Chem. Commun. 2018, 54, 10021-10035.

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(38) Highly luminescent lanthanide complexes sensitised by tertiary amide-linked carbostyril antennae. Kovacs, D.; Phipps, D.; Orthaber, A.; Borbas, K. E. Dalton Trans. 2018, 47, 10702-10714.

(37) The role of photoinduced electron transfer in the quenching of sensitized Europium emission. Kovacs, D.; Borbas, K. E. Coord. Chem. Rev. 2018, 364, 1-9.

(36) Rational synthesis of 2-bromoporphyrins and 2,12-dibromoporphyrins. Bornhof, A.-B.; Xiong, R.; Borbas, K. E. J. Org. Chem. 2017, 82, 12908-12913.

(35) Photophysics of coumarin and carbostyril-sensitized luminescent lanthanide complexes: Implications for complex design in multiplex detection. Kovacs, D.; Lu, X.; Mészáros, L. S.; Ott, M.; Andres, J.; Borbas, K. E. J. Am. Chem. Soc. 2017, 139, 5756-5767.

(34) Synthesis and characterization of ferrocenyl-chlorins, 1,1’-ferrocene-linked chlorin dimers and their BODIPY analogues. Arkhypchuk, A. I.; Orthaber, A.; Borbas, K. E. Inorg. Chem. 201756 (5), 3044-3054.

(33) Furan- and thiophene-based auxochromes red-shift chlorin absorptions and enable oxidative chlorin polymerizations. Xiong, R.; Bornhof, A.-B.; Arkhypchuk, A. I.; Orthaber, A.; Borbas, K. E. Chem. Eur. J. 201723, 40894095.

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(32) Synthesis and photophysical characterization of luminescent lanthanide complexes of nucleotide-functionalized cyclen- and dipicolinate-based ligands. Vithanarachchi, S. M.; Kovacs, D.; Borbas, K. E. Inorg. Chim. Acta. 2017, 460, 148-158.

  • Invited paper for the 50th anniversary issue ‘Inorganic Chemistry – The Next Generation‘.

(31) Directly linked hydroporphyrin dimers. Xiong, R.; Arkhypchuk, A. I.; Kovacs, D.; Orthaber, A.; Borbas, K. E. Chem. Commun. 2016, 52, 9056-9058.

  • Invited for the 2016 Emerging Investigators Issue of Chem. Commun.

(30) Expanding the versatility of dipicolinate-based luminescent lanthanide complexes: a fast method for antenna testing. Andres, J.; Borbas, K. E. Inorg. Chem. 2015, 54, 8174-8176.

(29) A light-switched yin and yang pair. Ottosson, H.; Borbas, K. E. Nature Chem. 2015, 7, 373-375.

(28) Multiplex detection of enzymatic activity with responsive lanthanide-based luminescent probes. Pershagen, E.; Borbas, K. E. Angew. Chem. Int. Ed. 2015, 54, 1787-1790

(27) Synthesis and characterisation of lanthanide-hydroporphyrin dyads. Xiong, R.; Andres, J.; Scheffler, K.; Borbas, K. E. Dalton Trans. 2015, 44, 2541-2553.

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(26) Mild microwave-assisted synthesis of dipyrromethanes and their analogues. Xiong, R.; Borbas, K. E. Synlett 2015, 26, 484-488 (special issue for the 6th EuCheMS Young Investigators Workshop).

(25) Designing reactivity-based responsive lanthanide probes for multicolor detection in biological systems. Pershagen, E.; Borbas, K. E. Coord. Chem. Rev. 2014, 273, 30-46 (invited contribution).

(24) A versatile long-wavelength-absorbing scaffold for Eu-based responsive probes. Szíjjártó, C.; Pershagen, E.; Ilchenko, N. O.; Borbas, K. E. Chem. Eur. J. 2013, 19, 3099-3109.

(23) Synthesis of chlorin-sensitized near IR-emitting lanthanide complexes. Laakso, J.; Rosser, G.; Szíjjártó, C.; Beeby, A.; Borbas, K. E. Inorg. Chem. 2012, 51, 10366-10374.

(22) Functionalisation of lanthanide complexes via microwave-enhanced Cu(I)-catalysed azide-alkyne cycloaddition. Szíjjártó, C.; Pershagen, E.; Borbas, K. E. Dalton Trans. 2012, 41, 7660-7669.

(21) Luminescent lanthanide complexes with analyte-triggered antenna formation. Pershagen, E.; Nordholm, J.; Borbas, K. E. J. Am. Chem. Soc. 2012, 134(24), 9832–9835.

Post doc

(20) Sahin, T.; Vairaprakash, P.; Borbas, K. E.; Balasubramanian, T.; Lindsey, J. S. Hydrophilic bioconjugatable trans-AB-porphyrins and peptide conjugates. J. Porphyrins Phthalocyanines, 2015, 19, 663-678.

(19) Cumpstey, I.; Ramstadius, C.; Borbas, K. E.; Alonzi, D. S.; Butters, T. D. Synthesis and a-Glucosidase II inhibitory activity of valienamine pseudodisaccharides relevant to N-glycan biosynthesis. Bioorg. Med. Chem. Lett. 2011, 21(8), 5219-5223.

(18) Cumpstey, I.; Ramstadius, C.; Borbas, K. E. Investigation of coupling reactions for the synthesis of valienamine pseudodisaccharides. Synlett 2011, 12, 1701-1704.

(17) Cumpstey, I.; Agrawal, S.; Borbas, K. E.; Martin-Matute, B. Iridium-catalysed condensation of alcohols and amines as a method for aminosugar synthesis. Chem. Commun. 2011, 47(27), 7827-7829.

(16) Mroz, P.; Huang, Y.-Y.; Szokalska, A.; Zhiyentayev, T.; Janjua, S.; Nifli, A.-P.; Sherwood, M. E.; Ruzie, C.; Borbas, K. E.; Fan, D.; Krayer, M.; Balasubramanian, T.; Yang, E.; Kee, H. L.; Kirmaier, C.; Diers, J. R.; Bocian, D. F.; Holten, D.; Lindsey, J. S.; Hamblin, M. R. Stable synthetic bacteriochlorins overcome the resistance of melanoma to photodynamic therapy. FASEB J. 2010, 24(9), 3160-3170.

(15)  Huang, Y.-Y.; Mroz, P.; Zhiyentayev, T.; Sharma, S. K.; Balasubramanian, T.; Ruzie, C.; Krayer, M.; Fan, D.; Borbas, K. E.; Yang, E.; Kee, H. L.; Kirmaier, C.; Diers, J. R.; Bocian, D. F.; Holten, D.; Lindsey, J. S.; Hamblin, M. R.  In vitro photodynamic therapy and quantitative structure-activity relationship studies with stable synthetic near-infrared-absorbing bacteriochlorin photosensitizers. J. Med. Chem. 2010, 53(10), 4018-4027.

(14) Cribiu, R.; Borbas, K. E.; Cumpstey, I. On the synthesis of vinyl and phenyl C-furanosides by stereospecific debenzylative cycloetherification. Tetrahedron 2009, 65(10), 2022-2031.

(13) Mroz, P.; Ying-Ying H.; Janjua, S.; Zhiyentayev, T.; Ruzie, C.; Borbas, K.E.; Dazhong Fan; Krayer, M.; Balasubramanian, T.; Eun Kyung Yang; Hooi Ling Kee; Holten, D.; Lindsey, J.S.; Hamblin, M.R., New stable synthetic bacteriochlorins for photodynamic therapy of melanoma. Proc. SPIEE 2009, 7380.

(12) Borbas, K. E.; Ruzie, C.; Lindsey, J. S. Swallowtail bacteriochlorins. Lipophilic absorbers for the near-infrared. Org. Lett. 2008, 10(10), 1931-1934.

(11) Borbas, K. E.; Chandrashaker, V.; Muthiah, C.; Kee, H. L.; Holten, D.; Lindsey, J. S.  Design, synthesis, and photophysical characterization of water-soluble chlorins. J. Org. Chem. 2008, 73(8), 3145-3158.

(10) Borbas, K. E.; Kee, H. L.; Holten, D.; Lindsey, J. S. A compact water-soluble porphyrin bearing an iodoacetamido bioconjugatable site. Org. Biomol. Chem. 2008, 6(1), 187-194.

(9)  Yao, Z.; Borbas, K. E.; Lindsey, J. S. Soluble precipitable porphyrins for use in targeted molecular brachytherapy. New J. Chem. 2008, 32(3), 436-451.

(8)  Bhaumik, J.; Yao, Z.; Borbas, K. E.; Taniguchi, M.; Lindsey, J. S.  Masked imidazolyl-dipyrromethanes in the synthesis of imidazole-substituted porphyrins. J. Org. Chem. 2006, 71(23), 8807-8817.

(7) Borbas, K.E.; Mroz, P.; Hamblin, M.R.; Lindsey, J.S., Bioconjugatable porphyrins bearing a compact swallowtail motif for water solubility, Bioconjugate Chem. 2006, 17(3), 638-653.

PhD

(6) Borbas, K. E.; Ferreira, C. S. M.; Perkins, A.; Bruce, J. I.; Missailidis, S. Design and synthesis of mono- and multimeric targeted radiopharmaceuticals based on novel cyclen ligands coupled to Anti-MUC1 aptamers for the diagnostic imaging and targeted radiotherapy of cancer. Bioconjugate Chem. 2007, 18(4), 1205-1212.

(5) Borbas, K. E.; Bruce, James I.  Synthesis of asymmetrically substituted cyclen-based ligands for the controlled sensitisation of lanthanides. Org. Biomol. Chem. 2007, 5(14), 2274-2282.

(4) Bodi, A.; Borbas, K. E.*; Bruce, J. I. Near IR-emitting DNA-probes exploiting stepwise energy transfer processes. Dalton Trans. 2007, 38, 4352-4358. (*corresponding author)

(3) Borbas, K. E.; Bruce, J. I. Synthesis of asymmetrically substituted 1,4,7,10-tetraazacyclododecanes for the triggered near infrared emission from lanthanide complexes, Chem. Commun. 2006,  44, 4596-4598.

(2) Missailidis S.; Thomaidou D.; Borbas K.E.; Price, M.R. Selection of aptamers with high affinity and high specificity against C595, an anti-MUC1 IgG3 monoclonal antibody, for antibody targeting. J. Immunol. Meth. 2005, 296( 1-2), 45-62.

Undergraduate

(1) Rabai, J.; Szabo, D.; Borbas, E. K.; Kovesi, I.; Kovesdi, I.; Csampai, A.; Gomory, A.; Pashinnik, V.E.; Shermolovich, Y.G. Practice of fluorous biphase chemistry: convenient synthesis of novel fluorophilic ethers via a Mitsunobu reaction. J. Fluorine Chem.  2002, 114(2), 199-207.